E-ISSN 2636-834X
 

Case Report 


Adverse Neuropsychiatric Events Associated with Varenicline: A Case Series

Burak Erman Menku, Taylan Altiparmak, Bahadir Genis, Behcet Cosar.

Abstract
Varenicline is an orally administered α4β2 nicotinic acetylcholine (Ach) receptor, partial agonist. This drug has been known to be more effective in the treatment of nicotine withdrawal than bupropion and nicotine replacement therapies. Besides this effectiveness, it has some systemic and neuropsychiatric side effects that physicians have been experienced often. Here, we aimed to draw attention to the possible neuropsychiatric risks of varenicline use by discussing the symptoms, clinical course, and treatment methods of four patients who admitted to psychiatry and neurology outpatient clinics, had a history of the therapeutic dose of varenicline use, and developed neuropsychiatric side effects. The first case was about a panic attack, and the second case had headaches, sleepiness, and tremors. In the third case, a psychotic attack due to varenicline was observed while and in the last case, myoclonic seizure symptoms were seen. Little is known about neuropsychiatric side effects due to varenicline. Neurological and psychiatric side effects should be closely monitored, and patients should be evaluated in a multidisciplinary way. The patients in this study will help to better define the neuropsychiatric side effects due to varenicline.

Key words: Varenicline, Neuropsychiatric, Side Effects


 
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How to Cite this Article
Pubmed Style

BEM, TA, Genis B, Cosar B. Adverse Neuropsychiatric Events Associated with Varenicline: A Case Series. PBS. 2021; 11(1): 80-83. doi:10.5455/PBS.20201231094830


Web Style

BEM, TA, Genis B, Cosar B. Adverse Neuropsychiatric Events Associated with Varenicline: A Case Series. http://www.pbsciences.org/?mno=302645354 [Access: March 29, 2021]. doi:10.5455/PBS.20201231094830


AMA (American Medical Association) Style

BEM, TA, Genis B, Cosar B. Adverse Neuropsychiatric Events Associated with Varenicline: A Case Series. PBS. 2021; 11(1): 80-83. doi:10.5455/PBS.20201231094830



Vancouver/ICMJE Style

BEM, TA, Genis B, Cosar B. Adverse Neuropsychiatric Events Associated with Varenicline: A Case Series. PBS. (2021), [cited March 29, 2021]; 11(1): 80-83. doi:10.5455/PBS.20201231094830



Harvard Style

, B. E. M., , . T. A., Genis, . B. & Cosar, . B. (2021) Adverse Neuropsychiatric Events Associated with Varenicline: A Case Series. PBS, 11 (1), 80-83. doi:10.5455/PBS.20201231094830



Turabian Style

, Burak Erman Menku, Taylan Altiparmak, Bahadir Genis, and Behcet Cosar. 2021. Adverse Neuropsychiatric Events Associated with Varenicline: A Case Series. Psychiatry and Behavioral Sciences, 11 (1), 80-83. doi:10.5455/PBS.20201231094830



Chicago Style

, Burak Erman Menku, Taylan Altiparmak, Bahadir Genis, and Behcet Cosar. "Adverse Neuropsychiatric Events Associated with Varenicline: A Case Series." Psychiatry and Behavioral Sciences 11 (2021), 80-83. doi:10.5455/PBS.20201231094830



MLA (The Modern Language Association) Style

, Burak Erman Menku, Taylan Altiparmak, Bahadir Genis, and Behcet Cosar. "Adverse Neuropsychiatric Events Associated with Varenicline: A Case Series." Psychiatry and Behavioral Sciences 11.1 (2021), 80-83. Print. doi:10.5455/PBS.20201231094830



APA (American Psychological Association) Style

, B. E. M., , . T. A., Genis, . B. & Cosar, . B. (2021) Adverse Neuropsychiatric Events Associated with Varenicline: A Case Series. Psychiatry and Behavioral Sciences, 11 (1), 80-83. doi:10.5455/PBS.20201231094830