Article Type: Case Reports
Intermenstrual Vaginal Bleeding Due to Sertraline Treatment: A Case Report
Omer Asan, Erol Goka
Sertraline and other serotonin reuptake inhibitors are widely used in the treatment of psychiatric disorders such as anxiety disorders and depression. Hematological adverse effects related to sertraline are uncommon; most of the reported cases presented with vaginal bleeding, epistaxis, purpura, hematuria, and rectal bleeding. SSRIs may increase the risk of bleeding through different mechanisms. The most emphasized mechanism is lowering platelet aggregation by reducing serotonin reuptake in platelets. This report includes a case of intermenstrual vaginal bleeding due to the use of sertraline and a review of the relevant literature. We aimed to draw clinician’s attention to this side effect of SSRIs.

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Key words: Adverse effect, sertraline, vaginal bleeding.
Psychiatry and Behavioral Sciences 2019;9(3):139-142
Online ISSN: 2636-834X
Creative Commons License This work is licensed under a Creative Commons Attribution 3.0 Unported License