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Case Report 


Intermenstrual Vaginal Bleeding due to Sertraline Treatment, A Case Report and Review of the Literature

Ömer Asan, Erol Göka.


Abstract
Sertraline and other serotonin reuptake inhibitors are widely used in the treatment of psychiatric disorders such as anxiety disorders and depression. Hematological adverse effects related to sertraline are uncommon; most of the reported cases presented with vaginal bleeding, epistaxis, purpura, hematuria, and rectal bleeding. SSRIs may increase the risk of bleeding through different mechanisms. The most emphasized mechanism is lowering platelet aggregability by reducing serotonin reuptake in platelets. This report includes a case of intermenstrual vaginal bleeding due to the use of sertraline and a review of the relevant literature. We aimed to draw clinician’s attention to this side effect of SSRIs.
Key Words: Adverse Effect, Sertraline, Vaginal Bleeding

Key words: adverse effect, sertraline, vaginal bleeding


 
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How to Cite this Article
Pubmed Style

Asan O, Goka E. Intermenstrual Vaginal Bleeding due to Sertraline Treatment, A Case Report and Review of the Literature. PBS. 2019; 9(3): 139-142. doi:10.5455/PBS.20181006062238

Web Style

Asan O, Goka E. Intermenstrual Vaginal Bleeding due to Sertraline Treatment, A Case Report and Review of the Literature. https://www.pbsciences.org/?mno=11581 [Access: April 05, 2025]. doi:10.5455/PBS.20181006062238

AMA (American Medical Association) Style

Asan O, Goka E. Intermenstrual Vaginal Bleeding due to Sertraline Treatment, A Case Report and Review of the Literature. PBS. 2019; 9(3): 139-142. doi:10.5455/PBS.20181006062238


Vancouver/ICMJE Style

Asan O, Goka E. Intermenstrual Vaginal Bleeding due to Sertraline Treatment, A Case Report and Review of the Literature. PBS. (2019), [cited April 05, 2025]; 9(3): 139-142. doi:10.5455/PBS.20181006062238


Harvard Style

Asan, O. . & Goka, . E. . (2019) Intermenstrual Vaginal Bleeding due to Sertraline Treatment, A Case Report and Review of the Literature. PBS, 9 (3), 139-142. doi:10.5455/PBS.20181006062238


Turabian Style

Asan, Omer , and Erol Goka. 2019. Intermenstrual Vaginal Bleeding due to Sertraline Treatment, A Case Report and Review of the Literature. Psychiatry and Behavioral Sciences, 9 (3), 139-142. doi:10.5455/PBS.20181006062238


Chicago Style

Asan, Omer , and Erol Goka. "Intermenstrual Vaginal Bleeding due to Sertraline Treatment, A Case Report and Review of the Literature." Psychiatry and Behavioral Sciences 9 (2019), 139-142. doi:10.5455/PBS.20181006062238


MLA (The Modern Language Association) Style

Asan, Omer , and Erol Goka. "Intermenstrual Vaginal Bleeding due to Sertraline Treatment, A Case Report and Review of the Literature." Psychiatry and Behavioral Sciences 9.3 (2019), 139-142. Print. doi:10.5455/PBS.20181006062238


APA (American Psychological Association) Style

Asan, O. . & Goka, . E. . (2019) Intermenstrual Vaginal Bleeding due to Sertraline Treatment, A Case Report and Review of the Literature. Psychiatry and Behavioral Sciences, 9 (3), 139-142. doi:10.5455/PBS.20181006062238


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