E-ISSN 2636-834X
 

Review Article 


The microbiota and gut-brain axis

Melina Kraus, Mesut Çetin, Feyza Arıcioğlu.

Abstract
The ability of gut microbiota to communicate with the brain and hence modulate behavior is an emerging novel concept in health and disease. The enteric microbiota interacts with the host to form essential relationships that govern homeostasis. Although enteric bacterial fingerprint of each individual is quite unique, there appears to be a certain balance that confers individual’s health benefits. A developing number of studies demonstrated that the microbiome of the human digestive tract might have had an effect on the elements of the focal anxious framework (CNS), through recognized pathways called the gut–brain axis. Recent data showed that the human microbiome ecosystem interfered with the brain’s development, central signaling systems, and behavior. It has been proposed that the disruption of the human microbiome may contribute to the etiology and course of some psychiatric disorders. Therefore, a decrease in the desirable gastrointestinal bacteria would lead to deterioration in gastrointestinal, neuroendocrine, immune functioning and consequently an illness. This review article presents an overview about the main pathways of the gut-brain axis and consequences of stress to the individual components.

Key words: brain-gut axis, microbiota, probiotics, anxiety disorders


 
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How to Cite this Article
Pubmed Style

Melina Kraus, Mesut Cetin, Feyza Arıcioğlu. The microbiota and gut-brain axis. PBS. 2016; 6(3): 172-9. doi:10.5455/jmood.20161004082122


Web Style

Melina Kraus, Mesut Cetin, Feyza Arıcioğlu. The microbiota and gut-brain axis. https://www.pbsciences.org/?mno=244660 [Access: December 15, 2023]. doi:10.5455/jmood.20161004082122


AMA (American Medical Association) Style

Melina Kraus, Mesut Cetin, Feyza Arıcioğlu. The microbiota and gut-brain axis. PBS. 2016; 6(3): 172-9. doi:10.5455/jmood.20161004082122



Vancouver/ICMJE Style

Melina Kraus, Mesut Cetin, Feyza Arıcioğlu. The microbiota and gut-brain axis. PBS. (2016), [cited December 15, 2023]; 6(3): 172-9. doi:10.5455/jmood.20161004082122



Harvard Style

Melina Kraus, Mesut Cetin, Feyza Arıcioğlu (2016) The microbiota and gut-brain axis. PBS, 6 (3), 172-9. doi:10.5455/jmood.20161004082122



Turabian Style

Melina Kraus, Mesut Cetin, Feyza Arıcioğlu. 2016. The microbiota and gut-brain axis. Psychiatry and Behavioral Sciences, 6 (3), 172-9. doi:10.5455/jmood.20161004082122



Chicago Style

Melina Kraus, Mesut Cetin, Feyza Arıcioğlu. "The microbiota and gut-brain axis." Psychiatry and Behavioral Sciences 6 (2016), 172-9. doi:10.5455/jmood.20161004082122



MLA (The Modern Language Association) Style

Melina Kraus, Mesut Cetin, Feyza Arıcioğlu. "The microbiota and gut-brain axis." Psychiatry and Behavioral Sciences 6.3 (2016), 172-9. Print. doi:10.5455/jmood.20161004082122



APA (American Psychological Association) Style

Melina Kraus, Mesut Cetin, Feyza Arıcioğlu (2016) The microbiota and gut-brain axis. Psychiatry and Behavioral Sciences, 6 (3), 172-9. doi:10.5455/jmood.20161004082122