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Case Report 
PBS. 2017; 7(2): 128-30

doi: 10.5455/jmood.20170404040638


Angioedema caused by oral paliperidone augmentation in the major depressive disorder treatment: a case report

Cilem Bilginer.


Abstract
Angioedema is a rare but life-threatening condition characterized by swelling in subcutaneous tissues and mucosa. Paliperidone is an effective treatment option for treatment-resistant patients with depression. While the most common adverse effect caused by medication is headaches, it is also less likely to observe edema or anaphylactic reaction. In this case report, an adolescent diagnosed with major depression and suffered from angioedema following oral paliperidone augmentation during the treatment was presented. Edema regressed spontaneously about 24-30 hours following the last drug intake. No significant laboratory finding that could explain this condition was found. The patient no longer suffered from a similar problem following discontinuation of paliperidone. This case suggests that the clinician should be alerted against possible allergic reactions by reason of oral usage of paliperidone in adolescents and further studies are needed to explore the underlying mechanisms of allergic responses for these patients.

Key words: paliperidone, risperidone, angioedema, adolescent


 
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How to Cite this Article
Pubmed Style

Cilem Bilginer. Angioedema caused by oral paliperidone augmentation in the major depressive disorder treatment: a case report. PBS. 2017; 7(2): 128-30.

doi:10.5455/jmood.20170404040638

Web Style

Cilem Bilginer. Angioedema caused by oral paliperidone augmentation in the major depressive disorder treatment: a case report. https://www.pbsciences.org/?mno=258736 [Access: June 27, 2026].

doi:10.5455/jmood.20170404040638

AMA (American Medical Association) Style

Cilem Bilginer. Angioedema caused by oral paliperidone augmentation in the major depressive disorder treatment: a case report. PBS. 2017; 7(2): 128-30.


doi:10.5455/jmood.20170404040638

Vancouver/ICMJE Style

Cilem Bilginer. Angioedema caused by oral paliperidone augmentation in the major depressive disorder treatment: a case report. PBS. (2017), [cited June 27, 2026]; 7(2): 128-30.


doi:10.5455/jmood.20170404040638

Harvard Style

Cilem Bilginer (2017) Angioedema caused by oral paliperidone augmentation in the major depressive disorder treatment: a case report. PBS, 7 (2), 128-30.


doi:10.5455/jmood.20170404040638

Turabian Style

Cilem Bilginer. 2017. Angioedema caused by oral paliperidone augmentation in the major depressive disorder treatment: a case report. Psychiatry and Behavioral Sciences, 7 (2), 128-30.


doi:10.5455/jmood.20170404040638

Chicago Style

Cilem Bilginer. "Angioedema caused by oral paliperidone augmentation in the major depressive disorder treatment: a case report." Psychiatry and Behavioral Sciences 7 (2017), 128-30.


doi:10.5455/jmood.20170404040638

MLA (The Modern Language Association) Style

Cilem Bilginer. "Angioedema caused by oral paliperidone augmentation in the major depressive disorder treatment: a case report." Psychiatry and Behavioral Sciences 7.2 (2017), 128-30. Print.


doi:10.5455/jmood.20170404040638

APA (American Psychological Association) Style

Cilem Bilginer (2017) Angioedema caused by oral paliperidone augmentation in the major depressive disorder treatment: a case report. Psychiatry and Behavioral Sciences, 7 (2), 128-30.


doi:10.5455/jmood.20170404040638

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