E-ISSN 2636-834X
 

Original Research 


Oxidative parameters in bipolar patients treated with electroconvulsive therapy and pharmacotherapy

Mahmut Bulut, Abdurrahman Altındağ, Zeliha Deveci, M. Cemal Kaya, Feridun Bülbül, Abdullah Taşkın, Şengül Kocamer, Haluk A. Savaş.

Abstract
Electroconvulsive (ECT) is one of the most efficacious choice in the treatment of bipolar disorder. There is no study conducted on human being investigating the effect of ECT on oxidative balance in bipolar disorder. In the present study, we aimed to evaluate the oxidative parameters on bipolar inpatients who is treated with ECT and pharmacotherapy. 31 bipolar inpatients in psychiatry department of Gaziantep University and 35 healty volunteeers were included in the study. Total Antioxidant Status (TAS), Total Oxidant Status (TOS) of serum samples were measured and Oxidative Stress Index (OSI) were counted in Harran University Biochemistry Laboratory.
In all patient group, bipolar manic episode and depressive episode patients; before ECT and after ECT there was no significant difference for oxidative parameters. Before ECT, TAS levels in bipolar depressive episode patients were significantly lower than the control group (z=-2.614, p=0.009). But after ECT, there was no difference between these two groups (z=-1.558, p>0.05).
Before ECT, TOS levels in bipolar manic episode patients were significantly higher than the control group (z=-2.598, p=0.009); after ECT, there was no difference between these two groups (z=-0.910, p>0.05).
Finally, when compared with controls, in bipolar depressive episode patients TAS levels were increased with ECT and pharmacotheraphy and in bipolar manic episode patients TOS levels were decreased. For more comprehensive results new studies are needed.

Key words: bipolar disorder, electroconvulsive therapy, oxidative parameters, combined treatment, oxidative parameters


 
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How to Cite this Article
Pubmed Style

Mahmut Bulut, Abdurrahman Altındağ, Zeliha Deveci, M. Cemal Kaya, Feridun Bulbul, Abdullah Taşkın, Şengul Kocamer, Haluk A. Savaş. [Oxidative parameters in bipolar patients treated with electroconvulsive therapy and pharmacotherapy]. PBS. 2013; 3(3): 93-9. Turkish. doi:10.5455/jmood.20130402053002


Web Style

Mahmut Bulut, Abdurrahman Altındağ, Zeliha Deveci, M. Cemal Kaya, Feridun Bulbul, Abdullah Taşkın, Şengul Kocamer, Haluk A. Savaş. [Oxidative parameters in bipolar patients treated with electroconvulsive therapy and pharmacotherapy]. https://www.pbsciences.org/?mno=31923 [Access: December 04, 2023]. Turkish. doi:10.5455/jmood.20130402053002


AMA (American Medical Association) Style

Mahmut Bulut, Abdurrahman Altındağ, Zeliha Deveci, M. Cemal Kaya, Feridun Bulbul, Abdullah Taşkın, Şengul Kocamer, Haluk A. Savaş. [Oxidative parameters in bipolar patients treated with electroconvulsive therapy and pharmacotherapy]. PBS. 2013; 3(3): 93-9. Turkish. doi:10.5455/jmood.20130402053002



Vancouver/ICMJE Style

Mahmut Bulut, Abdurrahman Altındağ, Zeliha Deveci, M. Cemal Kaya, Feridun Bulbul, Abdullah Taşkın, Şengul Kocamer, Haluk A. Savaş. [Oxidative parameters in bipolar patients treated with electroconvulsive therapy and pharmacotherapy]. PBS. (2013), [cited December 04, 2023]; 3(3): 93-9. Turkish. doi:10.5455/jmood.20130402053002



Harvard Style

Mahmut Bulut, Abdurrahman Altındağ, Zeliha Deveci, M. Cemal Kaya, Feridun Bulbul, Abdullah Taşkın, Şengul Kocamer, Haluk A. Savaş (2013) [Oxidative parameters in bipolar patients treated with electroconvulsive therapy and pharmacotherapy]. PBS, 3 (3), 93-9. Turkish. doi:10.5455/jmood.20130402053002



Turabian Style

Mahmut Bulut, Abdurrahman Altındağ, Zeliha Deveci, M. Cemal Kaya, Feridun Bulbul, Abdullah Taşkın, Şengul Kocamer, Haluk A. Savaş. 2013. [Oxidative parameters in bipolar patients treated with electroconvulsive therapy and pharmacotherapy]. Psychiatry and Behavioral Sciences, 3 (3), 93-9. Turkish. doi:10.5455/jmood.20130402053002



Chicago Style

Mahmut Bulut, Abdurrahman Altındağ, Zeliha Deveci, M. Cemal Kaya, Feridun Bulbul, Abdullah Taşkın, Şengul Kocamer, Haluk A. Savaş. "[Oxidative parameters in bipolar patients treated with electroconvulsive therapy and pharmacotherapy]." Psychiatry and Behavioral Sciences 3 (2013), 93-9. Turkish. doi:10.5455/jmood.20130402053002



MLA (The Modern Language Association) Style

Mahmut Bulut, Abdurrahman Altındağ, Zeliha Deveci, M. Cemal Kaya, Feridun Bulbul, Abdullah Taşkın, Şengul Kocamer, Haluk A. Savaş. "[Oxidative parameters in bipolar patients treated with electroconvulsive therapy and pharmacotherapy]." Psychiatry and Behavioral Sciences 3.3 (2013), 93-9. Print.Turkish. doi:10.5455/jmood.20130402053002



APA (American Psychological Association) Style

Mahmut Bulut, Abdurrahman Altındağ, Zeliha Deveci, M. Cemal Kaya, Feridun Bulbul, Abdullah Taşkın, Şengul Kocamer, Haluk A. Savaş (2013) [Oxidative parameters in bipolar patients treated with electroconvulsive therapy and pharmacotherapy]. Psychiatry and Behavioral Sciences, 3 (3), 93-9. Turkish. doi:10.5455/jmood.20130402053002