E-ISSN 2636-834X
 

Review Article 


Bipolar disorder and inflammation

Tevfik Kalelioğlu, Abdullah Genç, Nesrin Karamustafalıoğlu.

Abstract
There is growing number of researches showing evidence about the role of inflammation in pathophysiology of bipolar disorder. Besides inflammation in central nervous system, systemic inflammation is also thought to be associated with the acute and euthymic episodes and clinical outcome of illness. In this reviewö we firstly focus on the quantitative and structural changes in immune cells and their relationship with the illness episodes. Also cytokines, which have an important role in inflammation and are measurable in systemic circulation, are summarized. In addition to changes of inflammatory markers in different episodes of bipolar disorder, we mention the effect of bipolar disorder treatments on these markers. Acute phase proteins, which are produced and induced by the effect of cytokines, are also reviewed. Finally, we discuss the role of anti-inflammatory agents in treatment of bipolar disorder and offer suggestions about future researches.

Key words: bipolar disorder, inflammation, cytokines, immune system, inflammatory biomarkers


 
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How to Cite this Article
Pubmed Style

Tevfik Kalelioğlu, Abdullah Genc, Nesrin Karamustafalıoğlu. [Bipolar disorder and inflammation]. PBS. 2017; 7(1): 54-64. Turkish. doi:10.5455/jmood.20170203100427


Web Style

Tevfik Kalelioğlu, Abdullah Genc, Nesrin Karamustafalıoğlu. [Bipolar disorder and inflammation]. https://www.pbsciences.org/?mno=230938 [Access: December 16, 2023]. Turkish. doi:10.5455/jmood.20170203100427


AMA (American Medical Association) Style

Tevfik Kalelioğlu, Abdullah Genc, Nesrin Karamustafalıoğlu. [Bipolar disorder and inflammation]. PBS. 2017; 7(1): 54-64. Turkish. doi:10.5455/jmood.20170203100427



Vancouver/ICMJE Style

Tevfik Kalelioğlu, Abdullah Genc, Nesrin Karamustafalıoğlu. [Bipolar disorder and inflammation]. PBS. (2017), [cited December 16, 2023]; 7(1): 54-64. Turkish. doi:10.5455/jmood.20170203100427



Harvard Style

Tevfik Kalelioğlu, Abdullah Genc, Nesrin Karamustafalıoğlu (2017) [Bipolar disorder and inflammation]. PBS, 7 (1), 54-64. Turkish. doi:10.5455/jmood.20170203100427



Turabian Style

Tevfik Kalelioğlu, Abdullah Genc, Nesrin Karamustafalıoğlu. 2017. [Bipolar disorder and inflammation]. Psychiatry and Behavioral Sciences, 7 (1), 54-64. Turkish. doi:10.5455/jmood.20170203100427



Chicago Style

Tevfik Kalelioğlu, Abdullah Genc, Nesrin Karamustafalıoğlu. "[Bipolar disorder and inflammation]." Psychiatry and Behavioral Sciences 7 (2017), 54-64. Turkish. doi:10.5455/jmood.20170203100427



MLA (The Modern Language Association) Style

Tevfik Kalelioğlu, Abdullah Genc, Nesrin Karamustafalıoğlu. "[Bipolar disorder and inflammation]." Psychiatry and Behavioral Sciences 7.1 (2017), 54-64. Print.Turkish. doi:10.5455/jmood.20170203100427



APA (American Psychological Association) Style

Tevfik Kalelioğlu, Abdullah Genc, Nesrin Karamustafalıoğlu (2017) [Bipolar disorder and inflammation]. Psychiatry and Behavioral Sciences, 7 (1), 54-64. Turkish. doi:10.5455/jmood.20170203100427